While LBBB in older individuals and those with underlying heart disease is associated with increased mortality, it appears to have minimal effects on outcomes in younger, apparently healthy subjects. However, an isolated LBBB is occasionally found in individuals without clinically-detectable cardiovascular disease (CVD). LBBB is often associated with underlying cardiovascular abnormalities such as coronary artery disease, hypertension, or dilated cardiomyopathy.

The prevalence of left bundle-branch block (LBBB) in the general population has been estimated to range from 0.2 to 1.1%. These data may be useful toward the clinical interpretation of imaging studies performed on patients with an isolated LBBB. ConclusionsĪdults with an isolated LBBB have greater LV volumes and markedly reduced LVEF, despite the absence of overt cardiovascular disease. LV stroke volume, cardiac output, and mass, and all RV parameters were similar (p = NS) between the groups. LVEF in isolated LBBB was nearly two standard deviations (Z = − 1.95) below mean sex and age-matched group values. 68+/− 6% p <0.001) with similar myocardial contraction fraction. An isolated LBBB was associated with larger LV end-diastolic and end-systolic volumes (both p < 0.01) and lower LVEF (56+/− 7% vs. Isolated-LBBB subjects ( n = 18, 10F) ranged in age from 37 to 82 years. Isolated-LBBB cases were compared with matched controls using Wilcoxon paired signed-rank test, and to normative reference values via Z-score. All study subjects were scanned using the same CMR hardware and imaging sequence. Age-, sex-, hypertension-status, and body-surface area (BSA)-matched controls were identified from the Offspring cohort. We reviewed our clinical echocardiography database and the Framingham Heart Study Offspring cohort CMR database to identify adults with an isolated LBBB. The objective of this study was to compare LV and right ventricular (RV) volumes and EF in adults with an isolated LBBB to matched healthy controls and to population-derived normative values, using cardiovascular magnetic resonance (CMR) imaging. in the absence of cardiovascular dissease) LBBB on biventricular volumes and ejection fraction (EF) is not well characterized. Left bundle branch block (LBBB) is associated with abnormal left ventricular (LV) contraction, and is frequently associated with co-morbid cardiovascular disease, but the effect of an isolated (i.e.

Bundle branch block ivcd